Scott, I havent hunted them, but most places Ive checked into for a hunt recommend or insist on at least a .300 mag
Im hoping to hunt them one day but the biggest gun in the house is my wifes .30-06...which I would use without hesitation.
Texanss can be funny...most Ive run into recommend the .300 WSM for their whitetails.......

"...the left considers you vermin, and they'll kill you given the chance..." Bristoe