Hagel found the 175 Nosler out of a Mashburn went deeper than any other combo... So something like the 280 would do the job..
That is still a wicked combo. The 175 Partition or BBC is pretty danged tough on elk.
I've never used anything more than a 160 NP from the .280 - Love it !
I can sure see a 175 NP being truly wicked from a 28 Nosler though.