Mark,
If instead of comparing 200 NPTs with 150 NPTs sighted in at any particular range, you select instead the maximum point blank range for each (3" maximum above a scoped line of sight in each case), the 150 ends up sightes in at a longer range than the 200 and the diference in trajectories becomes much greater.
It's even greater if you compare 150 spitzers with 220 grain round noses.
Short of bison, moose, or big bears I find it difficult to imagine a purpose in North America for the 220 grain bullet. I have killed a few pronghorn and deer with 150 grain Sierra cup-and-cores loaded to about 3000 in the 30-06 and found the penetration and expansion adequate for the purpose. My guess is that a 180 or 200 NPT spitzer would be ideal for elk.
