30 06 is one great caliber thats for sure. versatile as all hell especially when you are a handloader. if your going to own just one rifle an 06 is a great choice. you can load 150 grain bullets for laser flat trajectory or load 220 gr to hit hard up close, anything in between is hardly a bad choice either. i personally am not interested in owning one for whatever reason but if youve got one and like to shoot it youd be hard pressed to find a more ideal rifle for any game north america has to offer.