Somewhere around age 55, The light bulb came on...
Ditto here, same age.
At 49 I went to Africa and practiced for months beforehand with a .375 H&H. I'd fire between 50 and 80 rounds in an afternoon, several of those from prone. At 55 I realized that I didn't like shooting it at all.
Now at 59 a full power .30-06 is as much as I want to shoot, and not much of that. I load my ought sixes to .308 levels and my favorite fun load in my .270's is a 7mm-08 clone - a 130 grain bullet with enough IMR-4895 to send it out at 2800 fps.
I'm liking the .308 a lot these days for a "big gun".