I don't hunt with handguns. I've got a Reeder custom .44 Magnum Redhawk sitting way in the back of the safe that I would send down the road at a major discount if I didn't have my name engraved on the barrel. It is a boat anchor on my hip and I don't like shooting it. It just does something to a bone in my strong hand thumb even though I took some sandpaper to the fancy grip. I'd rather carry (and shoot) my 6-1/2 pound scoped .308 rifle than a 3 pound magnum handgun.
I can get 925 FPS MV out of a 255 grain hard cast lead .45 ACP +P fired in a 2 lb. Glock, and that is my outer limit on big bore handguns.
I would prefer the 45 ACP in the plastic pistol format to any .357 Mag revolver. Less blast and better or at least equal killing effect.
Hard to beat the S&W M&P or Glock or 1911 in 45 ACP as a wilderness defensive gun when loaded to the gills.
