I will be honest, I have never used a 45ACP for hunting, one time did do the coup degas on a White tail with a 357 mag. I do not really consider either that good for hunting. To me the 45ACP is a 50 yard weapon, the 357 Mag 75 yards. I have hit the steel plates with regularity with both beyond that however. Does not mean to me at least that they are good for hunting (deer)