I've taken elk with mine.
I have a friend who has hunted Africa several times and owns just two rifles. Both are pre 64 model 70s, one in 300 H&H and one in 375 H&H. On one of his trips he and the PH were looking for a nice kudu when they stumbled onto a very nice old cape buffalo bull. Cape buffalo was in his plans for that trip and the PH asked if he wanted the bull. My friend said yes but only had the 300 with 180 grain Partitions. The guide said take the shot. He had seen my friend shoot game before. He said that bull went down faster than the four he'd killed on prior hunts with his 375.
