In theory, just about anything. Mu uncle took his two lion back in the late 60s with (the horror!) a 270 w Winchester Silvertips. Personally, eland would be the limit for me.
Just 'cause you can, doesn't mean you should...
Your Uncle was probably an excellent marksman, knew what his gun would do and delivered the goods.
I'd be shooting my .375 H&H. I don't feel I'm good enough to try a lesser round...
DF
