Model70Guy,
Yep, as you say, "A high shoulder will drop game in a heap, but the TTSX is far from the only bullet that will do that."
I've seen it and done it with a bunch of bullets, including (gasp!) the dreaded Bergers, and even Federal "blue box" and Remington Core-Lokt factory ammo. My wife did it, very deliberately, with the heaviest-bodied Montana whitetail buck she's ever taken, using a .243 Winchester and a 100-grain Nosler Partition at a measly 2900 fps. The lousy Partition even went through both shoulders and the spine--and exited.
Ain't that the truth. I'm sort of at the point of wanting the softest bullet I dare instead the hardest I can get. Heresy; I know.
My second rifle on this trip was a .300 win with a favorite load with the 190 Accubond LR, and a hastily camp developed one with the 210 Hunting VLD. Spectacular wound channels and exits were the norm, even on shoulder shots at close range.