Hmmmmm, one more writer to write off.
After a couple hundred critters with cartridges ranging from 222 to 50 caliber muzzleloaders and most everything in between. Prairie dogs to elk, I am of the opinion that the 270 with a 130gr bullet, or that ballistic range of cartridges is about as good as you can get for deer sized game.
I personally do not like the 243 or the 7mm RM. Here is my experience with those two cartridges.
My first year deer hunting I shot a deer with a 243 and never recovered it, second year I shot a spike buck that did know it was shot...until it died, thought I missed. Then there was the fuggin idiot who talked down my 270 whick killed like Thor's Hammer
, while he went on to miss and wound multiple deer with his wonderful 7mm RM. That's my story and I'm sticking to it.