when selecting the grain weight do you take the twist rate into consideration? I read that a 1 in 10 is meant for lighter bullets 115 to 140 grains. My concern is that I am going for an elk and I am not sure 140 grain bullet would have enough knockdown power.
First, a point of grammar.
It's weight, not "grain weight". You don't say "pound weight", it's just weight.
Your 1 in 10 twist will handle any common bullet weight just fine.
If you want to go heavier, Shooter Proshop has the 160gr Partion blems on sale for Father's day. They are a forgiving bullet and a good place for a new reloader to start for elk loads.