I've had a couple of failures with 130gr Sierra SBT on deer where the bullet came apart on the shoulder and failed to penetrate all the way through in one piece, but only within 100 yards where velocity was still very high. (I've not had that problem with Speer, or Hornady in that weight and caliber and believe their jackets either stay together better with their "flat bases" or their jackets are a bit thicker.) I've not had the same trouble with 150SBT or 150Spt (Speer) but always considered them for larger game than deer in that caliber whether "boat-tail" or flat base. (My "go-to-around-bullet" that seems to always work, "long or short", is the 150gr Nosler Partition; and IMO worth the extra cost for their consistent performance to use on any game where I would use a .270 Win.)
All the way through the deer, or just the shoulder?
