Many variables come into play, not the least of which is bullet selection and performance, but that's another topic entirely.. Considering heart-lung placement, the calibers mentioned and similar cartridges I have used: I have found that a deer that is undisturbed and unaware of my presence will often go right down at the shot, even when no bones larger than ribs are impacted. A deer that is on heightened alert and with adrenalin flowing may cover some distance before collapsing. Ditto for hogs, although if they run even 2-3 seconds, they tend to find the thickest and thorniest patch of brush to die in. Deer that run generally seem to follow known trails. Can't say the same for hogs.