At the end of the day - the critter computer (brain) dictates how fast they go down.

Immediate drops -
- direct brain / brain stem / neck nerve shots
- A shot at the vessels feeding the brain (kind of like when you stand up to fast and faint)
To get those you have to hit above the heart, there are check valves that keep the blood pressure up if you just take the heart out.

After that you have the bleed out - which depends on how long it takes to loose brain pressure

If you use a bow, you can “grunt” a buck after you shoot him and then you can watch things take place because he’ll stop and look for the buck that just poked him.