I like H110, Win 296 and 2400. I've loaded a lot of Unique too, Using Unique in my 4" 296 last summer - the dirt build up was incredible - so dirty the revolver did not function. Granted I took it PD shooting and shot more than 100 rounds without cleaning. I understand that Unique is supposed to be cleaner now though.
It sounds to me like you need to bump up your load some.