250 grain Nosler Accubonds!
He asked about dangerous game effectiveness, not mule deer effectiveness.
Also don't depend on 270 Speers; they're soft.
I dispatched a buffalo with a combination gun with the rife part 9,3X74R using a Woodleigh 286 solid. Had factory 286 Partition been available back then I would have used that, hands down. Anecdotal, but I was present when six A-Frames from a
9,3X64 Brenneke didn't do what was necessary on a BIG Masailand buffalo.
The bigger caliber Partitions are very good and tough, IMO.