The remage setup with a an 8 twist 22-250 would work, I have several PD rifles with criterion barrels. For 450 plus I prefer a fast twist 6mm though. I have an 8 twist 6BR and a 7 twist 6mm Creedmoor along with a stash of 105 Amax's that I prefer to the 22-250 when the wind is up and ranges get long.

This upcoming trip is probably going to burn through my stash of amaxs so I'm gonna have to find something else. I haven't heard good things about the 108 eldm that replaced them.