The bullet I have been loading in my 300 is a 180 gn Grand Slam. I have only shot Bucks that were 3 or older with them. Every deer I have shot has dropped at the shot and they don't even twitch. They don't bruise up the meat. Even if they hit big bones. A couple of the bucks were moving at a good clip when I shot chasing does and I hit them too far back and they still dropped dead. I have killed a bunch of deer with different guns and bullets and buckshot. Nothing I have used work like these yet.