I've only killed two elk with my .280 Remington in my old Remington 725, 22" bbl, Both were with a Nosler Partition, 160 grains in front of 54.0 grains of IMR 4350. Chronographed at 2880 FPS.

One shot kills. No more than a couple hundred yards. Both were standing approx. broadside. Worked for me. grin

L.W.

"Always go straight forward, and if you meet the devil, cut him in two and go between the pieces." (William Sturgis, clipper ship captain, 1830s.)