Just returned from six weeks in Africa. Used .375-270 TSX on five buffalo. All were taken with a single shot. Distance of shot and distance traveled are as follows: 85/25, 25/15, 105/85, 85/10, 18/105. The bullets worked perfectly at mv of 2675 FPS. All expanded to .800”.
I have been an advocate of the .416 bore but this has caused me to revise my thinking.