I still have and use an old Herter's measure....it throws as accurately as any of the others I have.

Ball powders are always quite uniform and such powders as IMR 4320 which is a short stick powder works quite uniformly.....I always look for SSC or SC on the courser powders.....such as IMR 7828 and 4831

At the range, I've not noticed any difference in +/-.5 and none of the deer or elk I've shot have noticed.....so I set my powder measure to the norm and check weigh a dozen consecutive loads to insure that I'm hitting somewhere around the middle and load ammo.....this has not ever caused me a problem.

To your question....ball powders run about +/- .2 grains and the courser powders run about +/- .5 grains.....My favorite powder measure is the Hornady.....