I have found that the same rifle/cartridge/bullet that works on deer at under 100 yards, will also work on deer at over 100 yards, and 200, and 300, and 400. As an example, for many years I hunted with one rifle.....a Remington 700 Classic in 270. I used 130 Sierra Gamekings, and killed deer from 25 yards to 450. No big deal either, it worked like it was supposed to.
