Go to 125gr Sierra PH and it's a nearly 300yard gun with a 10" deer-sized vital zone. At 300 I'd just hold on top of the shoulders.
Code
Calculated Table
Range	Drop	Drop	Windage	Windage	Velocity	Mach	Energy	Time	Lead	Lead
(yd)	(in)	(MOA)	(in)	(MOA)	(ft/s)	(none)	(ft•lbs)	(s)	(in)	(MOA)
0 	-1.5 	*** 	0.0 	*** 	2500.0 	2.239 	1734.4 	0.000 	0.0 	***
25 	0.6 	2.2 	0.1 	0.3 	2419.7 	2.167 	1624.8 	0.030 	5.4 	20.5
50 	2.3 	4.4 	0.4 	0.7 	2340.8 	2.097 	1520.6 	0.062 	10.9 	20.8
75 	3.6 	4.6 	0.8 	1.0 	2263.4 	2.027 	1421.6 	0.095 	16.6 	21.2
100 	4.5 	4.3 	1.5 	1.4 	2187.3 	1.959 	1327.7 	0.128 	22.6 	21.6
125 	4.9 	3.8 	2.3 	1.8 	2112.8 	1.892 	1238.7 	0.163 	28.7 	21.9
150 	4.9 	3.1 	3.4 	2.2 	2039.6 	1.827 	1154.5 	0.199 	35.1 	22.3
175 	4.3 	2.4 	4.7 	2.6 	1966.6 	1.761 	1073.3 	0.237 	41.7 	22.7
200 	3.2 	1.5 	6.3 	3.0 	1893.5 	1.696 	994.9 	0.276 	48.5 	23.2
225 	1.5 	0.6 	8.1 	3.4 	1822.1 	1.632 	921.3 	0.316 	55.6 	23.6
250 	-0.9 	-0.4 	10.2 	3.9 	1752.6 	1.570 	852.4 	0.358 	63.0 	24.1
275 	-4.0 	-1.4 	12.6 	4.4 	1685.1 	1.509 	788.0 	0.402 	70.7 	24.5
300 	-7.9 	-2.5 	15.3 	4.9 	1619.7 	1.451 	728.1 	0.447 	78.7 	25.0
325 	-12.6 	-3.7 	18.3 	5.4 	1556.6 	1.394 	672.4 	0.494 	87.0 	25.6
350 	-18.2 	-5.0 	21.7 	5.9 	1495.9 	1.340 	621.0 	0.543 	95.6 	26.1
375 	-24.8 	-6.3 	25.4 	6.5 	1437.8 	1.288 	573.7 	0.595 	104.6 	26.6
400 	-32.4 	-7.7 	29.5 	7.0 	1382.5 	1.238 	530.4 	0.648 	114.0 	27.2

Politics is War by Other Means