Just read an article that says that the permanent wound channel between 9mm, 40SW, and 45ACP is indistinguishable to surgeons or medical examiners. In addition the article states that 6 out of 7 handgun shootings are not lethal. I am inclined to believe if 12-13 inches of penetration from a HP is made regardless of caliber that the permanent wound cavities are going to be about the same. With the hit ratio for the police shootings being only 20% of fired bullets one would think that a more controllable pistol with more ammunition would be favored over a larger bore, higher recoiling, holding less ammunition pistol.