If I were going to limit my shots to 50-75 yds the .22 Magnum is a pretty good bone cruncher,but the accuracy of the .17 HMR along with the added velocity makes it a better choice past that range, just plan on head shots past 100 yds.
My best with the .22 was 125yds, with the .17 it was 238yds according to the rangefinder, with an intentional head shot.
