I’ve hunted mostly by lots of glassing and stalking. Too old now for too much strenuous hiking. I’ve personally taken elk with a 7mm Remington, 300 Win, 300 Rum, & 338 WM, I’ve been with my son, son in laws, and good friends when they used 7mm STW, 30-06, 280 Rem, 300 Jarrett and probably a few others I’ve forgotten about. Now days I’ll likely be packing my 300 Win or my 7mm STW. Bottom line is all big game calibers will work if shot is placed properly. Strong well constructed bullets built for penetration is a must for me.