With a 10" twist, I'd look at a 95-100gr NPT load for deer season and then switch to something lighter and more frangible for coyotes.
My own stainless .243win lives in my truck and I shoot the 105 Hornady HPBT in it for everything. It's not used as a dedicated deer gun, but more of a "target of opportunity" gun, including practice on steel. That bullet has worked well enough on hogs, deer, and crows so far.
