222 was one of my favorite coyote hunting rifles, Rem 788. 50g Sierra high velocity spt and their lead tip Blitz loaded with H335 at 3400 fps, anchored coyotes really great!

I have not read of many people using H335, Remember that Walt Berger sat a bunch of records with this powder. Use a Rem 71/2 primer, CCI BR4, or a CCI 41 due to thick cups.