My all time favorite coyote load is a nosler 50BT pushed as fast as I can out of my 22-250. I used to use 4064 but 3-4 years back tried 8208 and will probably stick with that the rest of my days. The bullet pokes through the hide.... blows itself to bits and only the solid base comes out the other side. Kills yoties very dead very quickly. I’ve used 55 sierras and hornady sp and they have blown huge holes going out the other side. Vmax have blown huge holes going IN. Ballistic tip seems to be just about right.