I have been hunting coyotes for about 60 years. I used the Sierra 53 gr. HP before they came out with the 52 gr. BTHP. The latter is very effective on coyotes out to about 350 yards with a well placed shot. But in extremely cold weather they don't open up as well. I have seen them run 300 plus yards before dropping. I used them in a Rem. 700 Varmint Special in the 22/250 caliber. The powder that I started out with was IMR 4320 and then switched to IMR 4064. I can't remember exactly, but I think that the load was 34 gr. of 4064. I killed hundreds of coyotes with that load. That caliber is a little tough on hides for fox.
