My grandmothers brother had it bad .contracted it in 1930's when he was a little kid,it twisted him up into a hunch back.one leg shorter,spine twisted,etc.
He became self employed and was as active as he could be.By the time he was in his mid 60's he was having trouble breathing,he passed out on his kitchen floor,never woke up.But my step dad and my father in law both had it and recovered from it and were fine.