Mostly no. I have 1 .22LR rifle zeroed at 100 yards, a Remington 37 with a 30x Lyman Super Targetspot.
All of my other .22LR rifles are zeroed at 50 yards.
Anything over 50 yards that I shoot with a rimfire is going to be shot with a .17HM2, .17HMR, 5MM RM, or .22MAG.
My .22s are used for plinking, understudy practice, woods loafing, or warming up before shooting centerfires, not for hunting.
I like to go out to our bottom ground timber and still-hunt black walnuts and cow turds.
