Kudu, if you can shoot the 416 well, I'd use that....Buff can be tough. A 375 can be adequate for perfect shots, although an 18" barrel will reduce velocity by 150-250 fps. If the recoil or follow-up capability is an issue, put a recoil reducer or weight in the buttstock. You never know what type of shot you'll be presented with out in the bush. I'd err on the heavy side on a $15,000 hunt.
