.375 250 TTSX has a BC of .424 and will go ~2800 FPS from a .375 H&H. For a well known "long-range" entity, the .375/250 @ 2800 will have a trajectory very similar to a 308Win w/168gn Sierra Match King. They're almost exactly the same drop @ 600yds and the 250 TTSX will drift about 2.75" more @ 600 < 1/2MOA wind drift difference between the two.
Food for thought.
