The last six or seven deer I've killed have been with the 6.5 CM. I'm hunting whitetails, and the bucks can sometimes field dress out at 200 pounds plus. I've used the 140 and 120 Nosler BT's, and the Sierra 120 grain soft points, the Prohunter, I believe. I've found the Sierra's to be my favorite bullet, but I also believe that any good hunting bullet would give similar results.