The TX 22 got very good reviews. One does not need tiny .22 pistol, something larger is ok. One has to be extremely limited in options to settle for .22lr as defensive weapon. Strike one smaller pistols tend to be less reliable. Strike two ammo failure rate is much higher than with center ignition cartridges, therefore, cartridge selection is extremely important. Most reliable are highest quality match loads. Strike three match grade ammo may not function in all semi-autos. The one shining ray of hope when it comes to semi-auto compatible ammo are CCI Minimags. Some years ago when I shot lot of .22 Kings of Duds were inexpensive Remington and Aguila loads.
This is were small light 8 or 9 shot .22 revolvers shine. It is far preferable to clear the dud by pressing trigger again then clearing a jam in semi-auto.
