(One of) My favorite Rifle(s) is my Winchester Model 70 Super Grade in wait for it...... 280 Remington.

Not only is it a nice looking rifle, it shoots my favorite 280 hand load: a 160g Federal TBT in Winchester brass over Reloader 26 at 2900 fps chronographed in 37 degree weather.

I also have a Model 70 Featherweight in 300 WSM so no need for a 30-06 here, but it's a fine cartridge. (As are most of them) I am also a big fan of the 7mm-08. (I have two of them)

If I couldn't load my own ammo, I'd likely favor something besides the 280 as it has been done a dis-service by Remington from the start and so factory ammo does not maximize it's potential at all.