RNF, no. I have read that the muzzle blast is more with N560 and also about secondary pressure spikes with the 500 series VV powder after the bullet leaves the barrel.

http://www.snipershide.com/forum/ubbthreads.php?ubb=showflat&Number=923087#Post923087

I have not noticed any difference with N560 and other powders that I have shot in this rifle. I am not sure if the 28 inches of barrel make any difference though.