Jeff-you know me, not overly technical here so I'll keep it that way.
On a light big game rifle, I'd go 2-8 Leo, on a rifle I was gonna shoot a lot from 500 on out and use on varmints as well then I'd go 3-10.
Side note, I'd save the money and go 6x36 and or 3-9 but that's just me.
Best of luck in your decision
Dober
