I have a 6-250 that I absolutely love and I'd highly recommend it to anyone who reloads.

Mine gives me fantastic accuracy using:

Sierra 60 gr HPs & IMR-4895 @ approx 3700 fps
Horn 75 gr HPs & RL15 @ approx 3250
Sierra 85 gr HPBT & Ramshot Hunter @ 3300 fps
90 gr NBT & RL15 @ 3k
90 gr Speer Hot Cor & Ramshot Hunter @ 3250

Crazy thing about my rifle is it puts all those (sub-MOA) loads into nearly identical POI so it is the ultimate multi-purpose game rifle.