If we are talking elk, the 7mm08 has some intrinsic advantage in that the bullets are bigger. If the question was posed between the .243 and .358, both based on the same case most everyone would agree that the .358 is the better elk round.
I guess I will be the odd guy in that I would unquestionably say the .243 win with VLDs is a better elk round than anything from the .358 win. I will admit a lack of experience with the .358 Win on elk but based on my .243 Win /105gr VLD experience it is hard to see how the .358 Win can be "better".
Pretty sure I would be hesitant to wade into a 600yd elk with the the .358 Win but the .243 Win/105gr VLD is pretty proven at that shot. I have done that and have been there.
I have also killed bulls at 100yds with the .243 Win /105gr VLD and can say there is little room for improvement.
