I've used TSXs on all my African hunts, in one caliber or other. I've also killed several hundred animals with them on 4 continents. Obviously they work.
"Working" is one thing, "best" is another. Since every bullet has a blend of different characteristics which often work against each other, and people have different ideas of what optimum is, best is just a matter of opinion. One man's best is another mans adequate. Passion to one is poison to another.
I can well imagine some PHs preferring a good bonded, hard hitting bullet like an Accubond over an extreme penetrating mono-bullet and just as easily can see others liking it the other way around. I myself fell out of love with TSXs a long time ago. That doesn't mean I hate them, but do prefer others most of the time.