Here is a question that will surely raise a heated discussion.
When still hunting and slowly working thru thick timber where a shot would be quick,do you have a round in the chamber?
Most often, but not always. I've been experimenting with carrying with an empty chamber and haveing the bolt raised, safety on with one in the chamber.
Coming to the conclusion that you will be able to get away with either as long as you are very familiar with your rifle. Not always, but most of the time. You may lose some close quick encounters, but for the majority I'm sure I can pull it off.
There is definitely merit to an empty chamber when it comes to safety.
Seriously considering selling some of the extras and buying a Blaser R8 rifle, which cocks on pushing the safety to the fire position. The system is a very safe one with one in the chamber.
Addition: If any others get close to me the bolt is raised and the chamber goes empty. Same thing sitting in a blind.
