I get the concept, I just can't see the need for a 375 H&H in North America. A "world battery" yes, NA no.
Brad all a 375 does is anything a 338 does...plus fits into the African scheme as well,
I don't know the difference between 338-250/225,and a 375 250/270. They cut the same swath.
I agree, Bob, and were I inclined to a Medium Bore I'd go to the 375 over the 338. However, I see no need for either, and would be more inclined to pair a heavier 300 Mag (or your Mahburn) to a lighter, smaller 270.
Lot's of ways to do this...
“Perfection is Achieved Not When There Is Nothing More to Add, But When There Is Nothing Left to Take Away” Antoine de Saint-Exupery