I have a 2008 Dodge 2500 6.7 Cummins 4x4 4-door that I pull my 5th wheel camper with. It has 127,000 miles and only had a few issues First; due to smog regs the EGR valve needs to be cleaned about every 65,000 miles or so, not a big deal and easy to do yourself. Second was the steering loosened up after about 100,000 miles, that is your steering wheel will have more play in it. There is a easy fix, about $150 for a brace/bottom bearing. Basically it puts a second bearing on the bottom of the steering box tightening it up and removing the play. I takes about 30 mins to put on.
I plan on keeping my truck until about 180,000 mile and then buying a new one.
