My wife is a fan of the 250 as well.
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Prairie dogs don't like it much.
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If I'm not mistaken, this is a 100gr interlock after going lengthwise about 6 inches down the spine of a small muley buck at about 75yds. I don't remember how much it weighed afterwords, may fifty something grains. I thought it did well all things considered.
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Stupidity is expensive
If you find yourself in a fair fight, your tactics suck!