I did exactly this over the past few months. I'm down to just my two centerfire rifles; a custom Rem 700 .264 Win Mag w/ blue printed action, long throat(as of yesterday), 27.5" Lilja #3 1:9, maple stock, glas bedded, teflon coated, etc. And my custom 700 .358 Norma Mag with 24" Douglas #3 barrel, 1:12 twist, glass bedded green w/ black B&C Alaska Hunter II stock, Shilen trigger, etc.
Pretty much got most the world that I'm likely to see covered with these two rifles for now.