It's more about accuracy in what load you should choose. Then I look at downrange performance.
I shoot:
180 gr in 300 win mag.
165 gr in .30-06
150 gr in .308
130 gr in .270
As somebody else pointed out, each caliber has a sweet spot. Why screw with it. Any of the above will smoke a deer and won't explode on impact from being driven at warp speed.
