I have the same Ruger m77 mII in 300wm, and hunted with it as my only big game rifle for 14+yrs. For the last 10yrs I used 180grn Hornady interlock at 2960-2980fps. It is a sturdy enough bullet to not give bloodshot meat, and still soft enough to open up decently on deer. The 190grn btsp was also a very accurate and solid performer.
I'm loading 180 interlock, 71.5 grns RL19, Win mag primers. Consistantly at or under 1moa, and purposefully under 3000fps.
I've taken deer out to 370yrds with my 300wm, but with the load that I use, it really isn't any more or less effective than a standard .270 deer load, which is perfect really. Just more recoil and noise to deal with.
If you go with one load and stick with it, you'll get to know the trajectory very well, and that is a big advantage.
If going to a TSX, I would recommend the 168grn and use it for everything.
